Study Design & Validity

S5E16 Simpson’s Paradox

In this week’s episode Greg and Patrick talk all about Simpson’s Paradox: what it is, examples of where it occurs in real life, and why we might not really need to think about it as a paradox at all.  Along the way they also discuss Apple Vision, The Simpsons  predicting the future, sitting too close

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S3E16: Your COVID Rapid Test Result: Are You Positive You’re Positive?

In today’s episode, Patrick and Greg use the context of COVID rapid tests to discuss issues of sensitivity, specificity, positive and negative predicted values, and the generally questionable utility of test accuracy information. Along the way they also discuss escape rooms, C4, Embassy Suites, palak paneer, 93% accurate, astragali, SAT prep courses, the volume of

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S3E10: Observation and Exploration

Patrick and Greg discuss the often forgotten importance of observation and exploration for the purpose of suggesting patterns and forming hypotheses, which can later be refined and rigorously tested within the framework of our well-developed confirmatory machinery. Along the they way they also discuss Orlando road trips, our inner child, crappy glue, melted chocolate, leaning

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S3E08: Statistical Degrees of Freedom…An Intimate Stranger

In today’s episode Patrick and Greg talk about statistical degrees of freedom: what they represent, how they are computed, and the importance they play in daily life. Along the way they also mention color blindness, the Skinnylicious menu, Kevin Bacon, Elmo’s Diner, the flatties, Amtrak, drinking Guinness at room temperature, sudoku, courage, paying the reaper,

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